Zotrim Study Proof
July 11th, 2009
Weight Loss Information: -
Zotrim has been independently investigated in five studies.
In summary, the 223 subjects that took Zotrim lost an average of 0.7 kg (1.5 lb) per each 10-day period.
In the key study1 47 overweight subjects took either Zotrim tablet or a placebo (dummy tablet) for 45 days.
Those taking Zotrim lost an average of 5.1 kg (11.2 lbs) whereas those taking placebo lost just 0.3 kg (0.7 lb).
In a shorter, placebo-controlled study1 with 44 overweight subjects, those taking Zotrim lost an average of 0.8 kg (1.8 lb) versus 0.3 kg (0.7 lb) for placebo over 10 days.
In three further ‘open’ label studies average weight-loss was:
• 2.3 kg over 28 days in 48 subjects wishing to loss weight2
• 1.8 kg over 28 days in 56 overweight women3
• 2.3 kg over 42 days in 73 overweight healthcare professionals4
In the most recent study4 it was reported that over the relatively short period of 42 days that 22% of subjects achieved a clinically significant loss of weight, equal to >5% of original body weight!
Weight Loss Management Data: -
A key success factor of any weight–loss regime is whether the weight loss is maintained or whether the weight lost is rapidly regained (the “yo-yo” effect’).
Zotrim has been shown to give lasting weight loss results:
23 subjects who had lost weight with Zotrim were studied for a further 12 months and instructed to take Zotrim again if they gained more than 1 kg1.
The group had almost the same average weight (72.5 kg) at the end of the 12 months as at the start (73kg)!
This demonstrates the effectiveness of Zotrim in weight loss management!
Slimmer Waistline Data: -
A slimmer waistline is a key objective of most dieters, but it is also increasingly used as an important indicator of risk of diseases such as heart disease with advice that men should have a waist measurement of less that 37cm and women less than 32 cm.
Two of the ‘open’ label studies with Zotrim investigated ‘waistline loss’
• 4.3 cm average waistline loss was achieved in 56 overweight women in 28 days3.
• 3.6 cm average waistline loss and 3.7 cm average hip measurement loss was achieved in 73 healthcare professionals over 42 days4.
Zotrim therefore helps users get into ‘great shape’.
Eating Control Data: -
There is significant evidence that Zotrim helps you to both eat less during meals and to snack less between meals. Our feeling of fullness (satiety) is controlled by links between the brain, nervous system and gastro-intestinal tract.
This includes ‘satiety’ signals that indicate when we have eaten enough and should stop eating. For example, a hormone called cholecystokinin (CCK) is released into the blood as food is digested, acts on receptors in the brain, which then slows the rate of stomach emptying.
The initial evidence for an effect of Zotrim was on slowing the rate of stomach emptying1. Using ultrasound studies with 7 subjects who drank 400 ml apple juice, the stomach emptied much more slowly (average 58 minutes) after taking one dose of Zotrim compared to then taking a placebo tablet (emptying in 38 minutes).
This indicated that Zotrim, by slowing the rate of stomach emptying, should make us feel fuller longer and stop snacking between meals.
This was supported by a study with 20 subjects, 10 of which took Zotrim and 10 of which took placebo for 20 days5. In the last week they were asked to record time to fullness during meals.
Perception of fullness occurred much sooner when taking Zotrim, for example, at lunch the average time to perceived fullness was decreased from 21.5 minutes to 12 minutes!
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